MR elastography as a method to estimate aortic stiffness and its comparison against MR based pulse wave velocity measurement
نویسندگان
چکیده
Background Arterial (aortic) stiffness is a well-recognized pathophysiological change that plays a significant role in the determination of risk factors for various cardiovascular diseases [1]. Measurement of arterial stiffness using pulse wave velocity (PWV) is the gold standard among non-invasive modalities. Recently, a novel non-invasive MRI based technique known as magnetic resonance elastography (MRE) was developed to determine the stiffness of the aorta[2]. The aim of the study is to compare the abdominal aortic stiffness obtained using MRI based PWV stiffness measurements against MRE based stiffness measurements.
منابع مشابه
Quantification of aortic stiffness using MR elastography and its comparison to MRI-based pulse wave velocity.
PURPOSE To determine the correlation in abdominal aortic stiffness obtained using magnetic resonance elastography (MRE) (μ(MRE)) and MRI-based pulse wave velocity (PWV) shear stiffness (μ(PWV)) estimates in normal volunteers of varying age, and also to determine the correlation between μ(MRE) and μ(PWV). MATERIALS AND METHODS In vivo aortic MRE and MRI were performed on 21 healthy volunteers ...
متن کاملReal time phase encoded MR for assessment of acute variability of central pulse wave velocity
Background The variability of pulse wave velocity (PWV) with changing arterial wall stress may reflect the degree of aortic stiffness independent of arterial pressure. We implemented a real-time MR flow technique so as to be able to assess acute changes in PWV due to affected arterial blood and/or intra thoracic pressure. The aim of this study was to assess the accuracy of rapid PWV assessment ...
متن کاملBiomarkers of hemodynamic stress and aortic stiffness post-STEMI: a cross-sectional analysis
Methods Fifty-four patients four months after acute STEMI were enrolled in this cross-sectional, single-center study. Nterminal pro B-type natriuretic peptide (NT-proBNP), mid-regional pro-A-type natriuretic peptide (MR-proANP) and mid-regional pro-adrenomedullin (MR-proADM) levels were measured by established assays. Aortic stiffness was assessed by the measurement of pulse wave velocity using...
متن کاملBiomarkers of Hemodynamic Stress and Aortic Stiffness after STEMI: A Cross-Sectional Analysis
AIM Increased aortic stiffness might adversely affect cardiac structure, function, and perfusion. Release of biomarkers of hemodynamic stress is thought to be enhanced by these alterations. We aimed to evaluate the association between biomarkers of hemodynamic stress and aortic stiffness assessed at a chronic stage after ST-segment elevation myocardial infarction (STEMI). METHODS Fifty-four p...
متن کاملComputer-assisted evaluation of aortic stiffness using data acquired via magnetic resonance.
Aortic stiffness is frequently assessed through pulse wave velocity (PWV) measurements. Based on data acquired by magnetic resonance (MR) using a one-dimensional time-of-flight technique, a new computational tool has been developed to rapidly construct flow velocity images and automatically calculate PWV. Comparison between PWV results obtained from this and a manual analysis demonstrates good ...
متن کامل